| Carl Junction Bulldogs | vs. Bolivar (Class 4 District 6 Semifinal) | Friday, Nov 6 at 7:00 PM |
| Carthage Tigers | vs. Republic (Class 5 District 6 Semifinal) | Friday, Nov 6 at 7:00 PM |
| Joplin Eagles | at Ozark Tigers (Class 6 District 5 Semifinal) | Friday, Nov 6 at 7:00 PM |
| Neosho Wildcats | vs. Branson (Class 5 District 6 Semifinal) | Friday, Nov 6 at 7:00 PM |
| New Heights Christian Academy | vs. Lockwood with Golden City (Class 1 District 1 8-Man) | Friday, Nov 6 at 7:00 PM |
| Seneca Indians | vs. Nevada (Class 3 District 6 Semifinal) | Friday, Nov 6 at 7:00 PM |
